The GcoPS method is dedicated to the co-localization of fluorescence image pairs for conventional and super-resolution microscopy. This fast procedure is controlled by a p-value and tests whether the Pearson correlation between two binary images is significantly positive. It amounts to quantifying the interaction strength by the area/volume of the intersection between the two binary images viewed as random distributions of geometrical objects. GcoPS handles 2D/3D images, variable SNRs and any kind of cell shapes.
This presentation is part of Minisymposium “MS66 - Spatial statistics in microscopy imaging”
organized by: Charles Kervrann (Inria) .